Compression neuropathy caused by cancer metastasis to the optic nerve canal

Hiroshi Tamai, Kazuyuki Ishida, Kensuke Murakami, Norio Narita, Teiji Tominaga, Nobuo Fuse

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Background: Cancerous cells are known to metastasize to different ocular structures. This happens especially to the choroid in males with lung cancer and females with breast cancer. However, we observed two cases of cancerous metastasis to the optic canal region. Both cases showed only a progressive decrease in vision without any other remarkable ophthalmological symptoms or abnormalities in the affected eye. Case presentation. Two females, a 60-year-old and a 73-year-old, came to our hospital because of progressive loss of vision. These patients showed no remarkable symptoms or signs in their eyes except visual acuity loss. Several ophthalmoscopic examinations, such as slit lamp microscopy and fundoscopy, showed no abnormal changes in their affected eye but magnetic resonance imaging indicated a massive legion around the optic nerve. Conclusion: It is possible for cancer to metastasize to the optic canal region and the existence of primary tumors should be considered.

Original languageEnglish
Article number546
JournalBMC Research Notes
Issue number1
Publication statusPublished - 2013 Dec 20


  • Cancer
  • Metastasis
  • Optic canal

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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