Complete separation of ternary mixture of amino acids using continuous rotating annular chromatography with partial recycling of effluent

Takuya Fukumura; Vinay M. Bhandari; Akio Kitakawa; Toshikuni Yonemoto

doi:10.1252/jcej.33.778

Complete separation of ternary mixture of amino acids using continuous rotating annular chromatography with partial recycling of effluent

Takuya Fukumura, Vinay M. Bhandari, Akio Kitakawa, Toshikuni Yonemoto

ENG - Chemical Engineering

Research output: Contribution to journal › Article

5 Citations (Scopus)

Abstract

Continuous rotating annular chromatography with partial recycling of the effluent (CRAC-PRE) was used for the separation of a ternary mixture of amino acids. A mathematical model describing the separation process was constructed to find the optimized operating conditions. The effectiveness of the CRAC-PRE for the separation of a ternary mixture was experimentally and theoretically elucidated by comparison to conventional CRAC. A recycling loop which gives reasonable separation was successfully arranged on the basis of the numerical simulation result. A combination of CRAC-PRE with the step elution method was applied to the complete separation of a ternary mixture of amino acids.

Original language	English
Pages (from-to)	778-784
Number of pages	7
Journal	JOURNAL of CHEMICAL ENGINEERING of JAPAN
Volume	33
Issue number	5
DOIs	https://doi.org/10.1252/jcej.33.778
Publication status	Published - 2000 Jan 1

Keywords

Amino acid
Complete separation
Partial recycling
Step elution
Ternary mixture

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

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Fukumura, T., Bhandari, V. M., Kitakawa, A., & Yonemoto, T. (2000). Complete separation of ternary mixture of amino acids using continuous rotating annular chromatography with partial recycling of effluent. JOURNAL of CHEMICAL ENGINEERING of JAPAN, 33(5), 778-784. https://doi.org/10.1252/jcej.33.778

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