Abstract
Continuous rotating annular chromatography with partial recycling of the effluent (CRAC-PRE) was used for the separation of a ternary mixture of amino acids. A mathematical model describing the separation process was constructed to find the optimized operating conditions. The effectiveness of the CRAC-PRE for the separation of a ternary mixture was experimentally and theoretically elucidated by comparison to conventional CRAC. A recycling loop which gives reasonable separation was successfully arranged on the basis of the numerical simulation result. A combination of CRAC-PRE with the step elution method was applied to the complete separation of a ternary mixture of amino acids.
Original language | English |
---|---|
Pages (from-to) | 778-784 |
Number of pages | 7 |
Journal | JOURNAL of CHEMICAL ENGINEERING of JAPAN |
Volume | 33 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2000 |
Keywords
- Amino acid
- Complete separation
- Partial recycling
- Step elution
- Ternary mixture
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)