Complete Separation of Amino Acids Using Continuous Rotating Annular Ion Exchange Chromatography with Partial Recycle of Effluent

Akio Kitakawa, Yoshihito Yamanishi, Toshikuni Yonemoto

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

A novel operational mode for continuous rotating annular chromatography for the complete separation of a binary mixture is proposed. In this mode, the effluents in which two solutes overlap are continuously recycled into the inlet of the packed bed, while the pure effluents are directly recovered. The recycling manners are determined on the basis of the results obtained in the preliminary experiments and numerical simulation without recycling. The model mixture of binary amino acids is completely separated by this process combined with the cation exchange method. The recovered concentrations of the amino acids are larger than those from the conventional method. The effects of some of the other operational conditions on the resolution are experimentally and theoretically investigated.

Original languageEnglish
Pages (from-to)3809-3814
Number of pages6
JournalIndustrial and Engineering Chemistry Research
Volume36
Issue number9
DOIs
Publication statusPublished - 1997 Sep

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Industrial and Manufacturing Engineering

Fingerprint Dive into the research topics of 'Complete Separation of Amino Acids Using Continuous Rotating Annular Ion Exchange Chromatography with Partial Recycle of Effluent'. Together they form a unique fingerprint.

Cite this