Complete Neurological Recovery in a Patient with Decerebrate Rigidity following Cardiac Arrest from Acute Airway Obstruction by Advanced Laryngeal Cancer

Hajime Furukawa, Shinji Takahashi, Taro Mizutani, Shin Nakayama, Tetsuro Wada, Hidenori Toyooka

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A 59-year-old man presented with severe dyspnea caused by advanced laryngeal cancer. As he had disregarded the dyspnea for a month, we did not have enough information about the extent of the tumor. The pulse oximter showed 88% with oxygen inhalation. Because of severe dyspnea, he could not maintain supine position. Fiberoptic laryngoscopy showed tumor bulk obstructing airway directly. In the operating room, at first, a cricothyroid membrane puncture was attempted under local anesthesia but the procedure was abandoned when the patient became hypoxic and unconscious. Immediately tracheostomy and cardiopulmonary resuscitation were performed. Tumor bulk had displaced the trachea and surrounding structures, making a tracheostomy difficult. Nine min after loss of consciousness, a secure airway was obtained. However, he was still unconscious and developed characteristic decerebrate rigidity. Therefore the patient was treated with infusion of thiamylal and free radical scavenger and mild hypothermia therapy (bladder temperature 34°C). On the fifth day of this treatment, after rewarming and discontinuation of thiamylal, the patient responded to command. He recovered with no neurological deficits. This case suggests that combined treatment with barbiturate, free radical scavenger, and mild hypothermia therapy is effective to minimize ischemic brain damage after cardiopulmonary resuscitation.

Original languageEnglish
Pages (from-to)294-297
Number of pages4
JournalJapanese Journal of Anesthesiology
Volume53
Issue number3
Publication statusPublished - 2004 Mar
Externally publishedYes

Keywords

  • Airway obstruction
  • Free radical scavenger
  • Hypothermic therapy
  • Laryngeal cancer
  • Resuscitation

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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