Comparisons of MEG, EEG, and ECoG source localization in neocortical partial epilepsy in humans

Nobukazu Nakasatp, Michel F. Levesque, Daniel S. Barth, Christoph Baumgartner, Robert L. Rogers, William W. Sutherling

Research output: Contribution to journalArticlepeer-review

161 Citations (Scopus)

Abstract

In order to delineate the characteristics of epileptic spikes, 1946 different spikes were studied in 6 patients with complex partial epilepsy. Non-invasive MEG and EEG source analyses of interictal spikes were contrasted to ECoG localization, surgical outcome and presence of lesions on MRI. Results indicated that: (1) using the most frequent occurring spike topography patterns from a large sample of spikes improved goodness-of-fit values for both MEG and EEG localization, (2) when spike patterns could be appropriately matched on several successive MEG measurements to provide an adequate matrix (3 of 6 subjects), there was excellent agreement between MEG dipole sources and ECoG sources as well as surgical outcome and presence of MRI lesions, (3) EEG sources analyse also gave good results but not as consistently as MEG.

Original languageEnglish
Pages (from-to)171-178
Number of pages8
JournalElectroencephalography and Clinical Neurophysiology
Volume91
Issue number3
DOIs
Publication statusPublished - 1994 Sep

Keywords

  • EEG
  • Electrocorticography
  • Magnetoencephalography
  • Neocortical partial epilepsy
  • Source localization

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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