Comparison of outcome of subtenon and intravitreal injection of triamcinolone acetonide for diabetic macular edema

Naoto Imadome, Hiroshi Kunikata, Shunichiro Asano, Hideyuki Konno, Takeshi Izumi, Toru Nakazawa

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Objective: To compare the effects of intravitreal triamcinolone acetonide (IVTA) and subTenon triamcinolone acetonide (STTA) injection for the treatment of diabetic macular edema (DME). Methods: In this retrospective series of 32 eyes of 25 patients with DME, 10 eyes underwent STTA (2011∼2012) and 22 eyes underwent IVTA (2013-2014) injection. Improvement in visual acuity (VA), central retinal thickness (CRT) and intraocular pressure (IOP) were assessed during 6 months after single TA treatment. Results: There was significant reduction in CRT 2-5 months post-STTA (4 months) and 1-6 months post-IVTA (6 months). There was also significant improvement in VA 2-4 months post-STTA (3 months) and 1-3 months post-IVTA(3 months). There was significant elevation in IOP 1-2 months post-IVTA(2 months), but not post-STTA. The period of enough reduction of CRT (蠆300 urn) was correlated with VA improvement after STTA (r=0.57, p=0.04), but not after IVTA (r=0.05. p=0.24). Conclusion: The therapeutic effect of TA for DME was unsustainable. It is possible that a different type of DME has a different effect with TA treatment.

Original languageEnglish
Pages (from-to)705-710
Number of pages6
JournalJapanese Journal of Clinical Ophthalmology
Volume69
Issue number5
Publication statusPublished - 2015 May 1

ASJC Scopus subject areas

  • Ophthalmology

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