Comparison of ionic and nonionic low-osmolar contrast media in coronary arteriography a crossover study in children

Haruo Saito; Kohji Kimura; Makoto Takamiya; Kazuo Yamamoto; Mitsushige Ohta; Hidetoshi Yamagami; Tetsuro Kamiya

doi:10.1097/00004424-198812000-00006

Comparison of ionic and nonionic low-osmolar contrast media in coronary arteriography a crossover study in children

Haruo Saito, Kohji Kimura, Makoto Takamiya, Kazuo Yamamoto, Mitsushige Ohta, Hidetoshi Yamagami, Tetsuro Kamiya

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Twenty-six patients with Kawasaki disease were observed in a prospective crossover study to compare coronary arteriography with a nonionic low-osmolar contrast medium, iopamidol 370 mgl/mL, and with an ionic low-osmolar contrast medium, ioxa-glate 320 mgI/mL. A slight heart rate change and no severe arrhythmia during coronary arteriography were observed with both agents. Electrocardiographically, QTc elongation and ST-T changes were marked in ioxaglate and minimal in iopamidol. No ventricular fibrillation occurred with either agent. Both contrast media provided adequate visualization for the diagnosis of Kawasaki disease, but the contrast of the images and the visualization of details were better with iopamidol than with ioxaglate. Iopamidol seems to be superior to ioxaglate in pediatric coronary arteriography.

Original language	English
Pages (from-to)	910-913
Number of pages	4
Journal	Investigative Radiology
Volume	23
Issue number	12
DOIs	https://doi.org/10.1097/00004424-198812000-00006
Publication status	Published - 1988 Dec
Externally published	Yes

Keywords

Children
Contrast media
Coronary arteriography
Kawasaki disease
Low osmolarity

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/00004424-198812000-00006

Cite this

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title = "Comparison of ionic and nonionic low-osmolar contrast media in coronary arteriography a crossover study in children",

abstract = "Twenty-six patients with Kawasaki disease were observed in a prospective crossover study to compare coronary arteriography with a nonionic low-osmolar contrast medium, iopamidol 370 mgl/mL, and with an ionic low-osmolar contrast medium, ioxa-glate 320 mgI/mL. A slight heart rate change and no severe arrhythmia during coronary arteriography were observed with both agents. Electrocardiographically, QTc elongation and ST-T changes were marked in ioxaglate and minimal in iopamidol. No ventricular fibrillation occurred with either agent. Both contrast media provided adequate visualization for the diagnosis of Kawasaki disease, but the contrast of the images and the visualization of details were better with iopamidol than with ioxaglate. Iopamidol seems to be superior to ioxaglate in pediatric coronary arteriography.",

keywords = "Children, Contrast media, Coronary arteriography, Kawasaki disease, Low osmolarity",

author = "Haruo Saito and Kohji Kimura and Makoto Takamiya and Kazuo Yamamoto and Mitsushige Ohta and Hidetoshi Yamagami and Tetsuro Kamiya",

year = "1988",

month = dec,

doi = "10.1097/00004424-198812000-00006",

language = "English",

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journal = "Investigative Radiology",

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T1 - Comparison of ionic and nonionic low-osmolar contrast media in coronary arteriography a crossover study in children

AU - Saito, Haruo

AU - Kimura, Kohji

AU - Takamiya, Makoto

AU - Yamamoto, Kazuo

AU - Ohta, Mitsushige

AU - Yamagami, Hidetoshi

AU - Kamiya, Tetsuro

PY - 1988/12

Y1 - 1988/12

N2 - Twenty-six patients with Kawasaki disease were observed in a prospective crossover study to compare coronary arteriography with a nonionic low-osmolar contrast medium, iopamidol 370 mgl/mL, and with an ionic low-osmolar contrast medium, ioxa-glate 320 mgI/mL. A slight heart rate change and no severe arrhythmia during coronary arteriography were observed with both agents. Electrocardiographically, QTc elongation and ST-T changes were marked in ioxaglate and minimal in iopamidol. No ventricular fibrillation occurred with either agent. Both contrast media provided adequate visualization for the diagnosis of Kawasaki disease, but the contrast of the images and the visualization of details were better with iopamidol than with ioxaglate. Iopamidol seems to be superior to ioxaglate in pediatric coronary arteriography.

AB - Twenty-six patients with Kawasaki disease were observed in a prospective crossover study to compare coronary arteriography with a nonionic low-osmolar contrast medium, iopamidol 370 mgl/mL, and with an ionic low-osmolar contrast medium, ioxa-glate 320 mgI/mL. A slight heart rate change and no severe arrhythmia during coronary arteriography were observed with both agents. Electrocardiographically, QTc elongation and ST-T changes were marked in ioxaglate and minimal in iopamidol. No ventricular fibrillation occurred with either agent. Both contrast media provided adequate visualization for the diagnosis of Kawasaki disease, but the contrast of the images and the visualization of details were better with iopamidol than with ioxaglate. Iopamidol seems to be superior to ioxaglate in pediatric coronary arteriography.

KW - Children

KW - Contrast media

KW - Coronary arteriography

KW - Kawasaki disease

KW - Low osmolarity

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JO - Investigative Radiology

JF - Investigative Radiology

SN - 0020-9996

IS - 12

ER -

Comparison of ionic and nonionic low-osmolar contrast media in coronary arteriography a crossover study in children

Abstract

Keywords

ASJC Scopus subject areas

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