Comparison of ionic and nonionic low-osmolar contrast media in coronary arteriography a crossover study in children

Haruo Saito, Kohji Kimura, Makoto Takamiya, Kazuo Yamamoto, Mitsushige Ohta, Hidetoshi Yamagami, Tetsuro Kamiya

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Twenty-six patients with Kawasaki disease were observed in a prospective crossover study to compare coronary arteriography with a nonionic low-osmolar contrast medium, iopamidol 370 mgl/mL, and with an ionic low-osmolar contrast medium, ioxa-glate 320 mgI/mL. A slight heart rate change and no severe arrhythmia during coronary arteriography were observed with both agents. Electrocardiographically, QTc elongation and ST-T changes were marked in ioxaglate and minimal in iopamidol. No ventricular fibrillation occurred with either agent. Both contrast media provided adequate visualization for the diagnosis of Kawasaki disease, but the contrast of the images and the visualization of details were better with iopamidol than with ioxaglate. Iopamidol seems to be superior to ioxaglate in pediatric coronary arteriography.

Original languageEnglish
Pages (from-to)910-913
Number of pages4
JournalInvestigative Radiology
Volume23
Issue number12
DOIs
Publication statusPublished - 1988 Dec
Externally publishedYes

Keywords

  • Children
  • Contrast media
  • Coronary arteriography
  • Kawasaki disease
  • Low osmolarity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Comparison of ionic and nonionic low-osmolar contrast media in coronary arteriography a crossover study in children'. Together they form a unique fingerprint.

Cite this