Abstract
Twenty-six patients with Kawasaki disease were observed in a prospective crossover study to compare coronary arteriography with a nonionic low-osmolar contrast medium, iopamidol 370 mgl/mL, and with an ionic low-osmolar contrast medium, ioxa-glate 320 mgI/mL. A slight heart rate change and no severe arrhythmia during coronary arteriography were observed with both agents. Electrocardiographically, QTc elongation and ST-T changes were marked in ioxaglate and minimal in iopamidol. No ventricular fibrillation occurred with either agent. Both contrast media provided adequate visualization for the diagnosis of Kawasaki disease, but the contrast of the images and the visualization of details were better with iopamidol than with ioxaglate. Iopamidol seems to be superior to ioxaglate in pediatric coronary arteriography.
Original language | English |
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Pages (from-to) | 910-913 |
Number of pages | 4 |
Journal | Investigative Radiology |
Volume | 23 |
Issue number | 12 |
DOIs | |
Publication status | Published - 1988 Dec |
Externally published | Yes |
Keywords
- Children
- Contrast media
- Coronary arteriography
- Kawasaki disease
- Low osmolarity
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging