Abstract
The aim of this study is to investigate in vivo local BMP-2 PK and bone induction in two bioceramics blocks (HAp, β-TCP), based on different composition and surface structures. We estimated the in vivo release profile of 125I-labeled BMP-2 and bone induction of hard tissues histologically. β-TCP is more effective for both BMP-2 retention and bone induction, compared to HAp, in the ectopic model.
Original language | English |
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Pages (from-to) | 1033-1036 |
Number of pages | 4 |
Journal | Key Engineering Materials |
Volume | 361-363 II |
Publication status | Published - 2008 |
Externally published | Yes |
Keywords
- BMP-2
- Dose-response
- HAp
- Release
- β-TCP
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering