Comparative study of FDG PET/CT and conventional imaging in the staging of rhabdomyosarcoma

Ukihide Tateishi, Ako Hosono, Atsushi Makimoto, Yuki Nakamoto, Tomohiro Kaneta, Hiroshi Fukuda, Koji Murakami, Takashi Terauchi, Tsuyoshi Suga, Tomio Inoue, Edmund E. Kim

    Research output: Contribution to journalArticlepeer-review

    86 Citations (Scopus)

    Abstract

    Objective: The current study was conducted to compare the diagnostic accuracy between 18F-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET)/computed tomography (CT), and conventional imaging (CI) for the staging and re-staging of patients with rhabdomyosarcomas. Methods: Thirty-five patients who underwent FDG PET/CT prior to treatment were evaluated retrospectively. CI methods consisted of 99mTc-hydroxymethylene diphosphonate bone scintigraphy, chest radiograph, whole body CT, and magnetic resonance imaging of the primary site. The images were reviewed and two boardcertified radiologists reached a diagnostic consensus. Tumor stage was confirmed by histological examination and/or follow-up examinations. Results: Interpretation on the basis of FDG PET/CT, and CI, diagnostic accuracies of the T and N stages were similar. Using FDG PET/CT, the M stage was correctly assigned in 31 patients (89%), whereas the accuracy of CI in M stage was 63%. TNM stage was correctly assessed with FDG PET/CT in 30 of 35 patients (86%) and with CI in 19 of 35 patients (54%). The overall TNM staging and M staging accuracies of FDG PET/CT were significantly higher than that of CI (P < 0.01). Conclusions: FDG PET/CT is more accurate than CI regarding clinical staging and re-staging of patients with rhabdomyosarcomas.

    Original languageEnglish
    Pages (from-to)155-161
    Number of pages7
    JournalAnnals of Nuclear Medicine
    Volume23
    Issue number2
    DOIs
    Publication statusPublished - 2009 Feb

    Keywords

    • FDG PET/CT
    • Rhabdomyosarcoma
    • Stage

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging

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