Comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1989): II. Background of patients

Yoshiaki Kumamoto, Takaoki Hirose, Noriaki Tanaka, Yoshinao Hikichi, Shiro Shigeta, Yasuo Shiraiwa, Hiroshi Kameoka, Hiroshi Yoshida, Masahiro Ogata, Hiroshi Tazaki, Hisami Iri, Hiroshi Uchida, Yoshio Kobayashi, Seiji Matsuda, Ryuichi Kitagawa, Makoto Fujime, Kazuhiko Fujita, Jun Igari, Toyoko Oguri, Nozomu KosakaiKeizo Yamaguchi, Chikako Mochida, Taro Furusawa, Yasuko Takeuchi, Hiromi Moriyama, Kikutaro Shibata, Seibun Yonezu, Minato Takaha, Kiyomi Matsumiya, Michio Tanaka, Mitsuo Kaku, Kazuyuki Sugawara

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Clinical background was investigated on 1,197 bacterial strains isolated from patients with urinary tract infections (UTIs) in 10 hospitals during the period from June, 1989 to May, 1990. 1. Distribution of sex and age A majority of female patients with UTIs accounted for a twenties and thirties. The proportion of male patients with UTI has increased with age, accounting for majority in patients 70 years or older. 2. Distribution of infection types and age Most cases among twenties or thirties were uncomplicated UTIs. Fifties and older cases were most frequent in complicated UTIs. 3. Distribution of isolated bacteria and age Escherichia coli was most frequent on the whole, followed by Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus spp. and Klebsiella spp. E. coli had declined with age, and on the other hand, E. faecalis and P. aeruginosa had increased with age. 4. Administration of antibiotics and pathogens isolated from UTIs In uncomplicated UTIs, pathogens, after administration of antibiotics, isolated from patients have obviously decreased from 439 to 4. Before an administration of antibiotics, E. coli was mainly detected, but after an administration of antibiotics, E. coli has decreased into two strains. After administration of antibiotics, pathogens of complicated UTIs, without indwelling catheter, have decreased from 324 to 19: E. coli has decleased from 86 to 2, but E. faecalis, Staphylococcus spp., Enterobacter spp. and P. aeruginosa have increased. Pathogens of complicated UTIs with indwelling catheter, have decreased from 156 to 14 after administration of antibiotics, and mainly isolated pathogens were E. faecalis and P. aeruginosa.

Original languageEnglish
Pages (from-to)1161-1173
Number of pages13
JournalThe Japanese Journal of Antibiotics
Volume48
Issue number9
DOIs
Publication statusPublished - 1995 Sep

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

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