Comparative Effects of Lingual and Facial Nerve Stimulation on Intracranial and Extracranial Vasomotor Responses in Anesthetized Cats

Minoru Sato, Hiroshi Izumi, Keishiro Karita, Naofumi Iwatsuki

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Electrical stimulaion of the central cut end of the lingual nerve (as reflex activation of parasympathetic nerve) or of the peripheral cut end of the facial (VIIth cranial) nerve (as direct activation of parasympathetic nerve) elicited the ipsilateral blood flow increases in lower lip, palate and common carotid artery (CCA) but not in frontal cerebral cortex in α-chloralose-urethane anesthetized, vagosympathectomized cats. No significant difference, in terms of the vasomotor changes examined, was found between lingual nerve and facial nerve stimulation. The results suggest that there is no somato-parasympathetic reflex vasodilator mechanism serving the frontal cerebral cortex, and that changes in CCA blood flow should not be taken to be indicative of blood flow changes in cerebrocortical blood flow However, we cannot entirely rule out the possibility of a neurogenic vasodilator influence of the facial pathway, since small blood flow increases in the frontal cerebral cortex were sometimes observed on facial nerve stimulation.

Original languageEnglish
Pages (from-to)103-113
Number of pages11
JournalTohoku Journal of Experimental Medicine
Volume182
Issue number2
DOIs
Publication statusPublished - 1997 Jun

Keywords

  • Cerebrocortical blood flow
  • Common carotid artery
  • Lip blood flow
  • Palate blood flow
  • Parasympathetic reflex vasodilation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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