Monte Carlo simulation is the most accurate tool for calculating dose distributions. In particular, the Electron Gamma shower computer code has been widely used for multi-purpose research in radiotherapy, but Monte Carlo GEANT4 (GEometry ANd Tracking) is rare for radiotherapy with photon beams and needs to be verified further under various irradiation conditions, particularly multi-leaf collimator-based intensity-modulated radiation therapy (MLC-based IMRT). In this study, GEANT4 was used for modeling of a 6 MV linac for dynamic MLC-based IMRT. To verify the modeling of our linac, we compared the calculated data with the measured depth-dose for a 10 × 10 cm2 field and the measured dose profile for a 35 × 35 cm2 field. Moreover, 120 MLCs were modeled on the GEANT4. Five tests of MLC modeling were performed: (I) MLC transmission, (II) MLC transmission profile including intra- and inter-leaf leakage, (III) tongue-and-groove leakage, (IV) a simple field with different field sizes by use of MLC and (V) a dynamic MLC-based IMRT field. For all tests, the calculations were compared with measurements of an ionization chamber and radiographic film. The calculations agreed with the measurements: MLC transmissions by calculations and measurements were 1.76 ± 0.01 and 1.87 ± 0.01 %, respectively. In gamma evaluation method (3 %/3 mm), the pass rates of the (IV) and (V) tests were 98.5 and 97.0 %, respectively. Furthermore, tongue-and-groove leakage could be calculated by GEANT4, and it agreed with the film measurements. The procedure of commissioning of dynamic MLC-based IMRT for GEANT4 is proposed in this study.
- Monte Carlo simulation
ASJC Scopus subject areas
- Physical Therapy, Sports Therapy and Rehabilitation
- Radiology Nuclear Medicine and imaging