Abstract
A fluorescein-spiropyran conjugate (2) behaves as a receptor for colorimetric sensing of cyanide anion (CN-) in aqueous media under irradiation of UV light. The compound 2, which exists as a spirocycle-closed (SP) form in the dark condition, is isomerized to the spirocycle-opened merocyanine (MC) form upon irradiation of UV light and shows absorption bands at 467 and 568 nm. Addition of CN- to the solution leads to a decrease in these bands and an appearance of new absorption band at 512 nm, via a nucleophilic interaction between CN- and the spirocarbon of MC form. This absorption change occurs selectively with CN- and enables ratiometric quantification of CN- by absorption analysis.
Original language | English |
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Pages (from-to) | 690-696 |
Number of pages | 7 |
Journal | Tetrahedron |
Volume | 68 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2012 Jan 14 |
Externally published | Yes |
Keywords
- Cyanide
- Fluorescein
- Receptor
- Spiropyran
- Water
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry