Collision tumor of anaplastic oligodendroglioma and gangliocytoma: A case report

Yoichi Takeuchi, Masayuki Kanamori, Toshihiro Kumabe, Ryuta Saito, Yukihiko Sonoda, Mika Watanabe, Teiji Tominaga

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

A 53-year-old woman presented with a rare case of coexistence of anaplastic oligodendroglioma with gangliocytoma manifesting as progressive disturbance of consciousness and left hemiparesis. Magnetic resonance imaging with gadolinium demonstrated the mass lesion consisted of a strongly enhanced area around the middle cerebral artery and less enhanced areas in the right temporal lobe, insula, and basal ganglia. She underwent subtotal resection of the tumor, resulting in improvement of her symptoms. Macroscopic and histological examination showed the tumor consisted of two distinct components, grayish soft tissue and yellowish hard tissue. The former consisted of cells with equal-sized round-to-oval hyperchromatic nuclei and perinuclear halo with microvascular proliferation and necrosis, and the diagnosis was anaplastic oligodendroglioma. The latter consisted of large and dysplastic neurons with marked nucleoli and basophilic cytoplasm containing Nissl bodies, with nonneoplastic glial cells in the stroma, and the diagnosis was gangliocytoma. Both lesions were distinct, but intermingled at the border. These two tumors apparently occurred as a collision tumor.

Original languageEnglish
Pages (from-to)89-93
Number of pages5
JournalBrain Tumor Pathology
Volume26
Issue number2
DOIs
Publication statusPublished - 2009 Oct

Keywords

  • Anaplastic oligodendroglioma
  • Coexistence
  • Gangliocytoma

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology
  • Cancer Research

Fingerprint Dive into the research topics of 'Collision tumor of anaplastic oligodendroglioma and gangliocytoma: A case report'. Together they form a unique fingerprint.

Cite this