Cognitive function in rats with alcohol ingestion

H. Sasaki, Y. Matsuzaki, T. Nakagawa, H. Arai, M. Yamama, K. Sekizawa, Y. Ikarashi, Y. Maruyama

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

The effect of alcohol ingestion on learning disturbances was tested in rats. Rats were fed either an alcohol solution or a nonalcohol solution. The concentration of acetylcholine in the whole brain was significantly lower in rats fed with alcohol than rats fed without alcohol. Passive avoidance learning shows a lower tendency in rats with alcohol compared to rats without alcohol, but the alcohol and control groups did not differ in passive avoidance learning. We suggest that alcohol may disturb acetylcholine metabolism in the brain.

Original languageEnglish
Pages (from-to)845-848
Number of pages4
JournalPharmacology, Biochemistry and Behavior
Volume52
Issue number4
DOIs
Publication statusPublished - 1995 Dec

Keywords

  • Acetylcholine
  • Alcohol
  • Cognitive function
  • Passive avoidance learning
  • Rats

ASJC Scopus subject areas

  • Biochemistry
  • Toxicology
  • Pharmacology
  • Clinical Biochemistry
  • Biological Psychiatry
  • Behavioral Neuroscience

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