Calcium is universal and versatile signal transduction molecule. Intracellular calcium is precisely regulated by various cellular mechanisms, making it possible to contribute to normal neuronal functions. Recently, the relationship between calcium and neuronal functions including cognitive functions has been investigated. This paper reviews normal and abnormal functions of calcium in a perspective of raveling the pathophysiology of neuropsychiatric disorders, such as Alzheimer's disease and Parkinson's disease. And, I introduce the slow calcium oscillation in striatum, which lasted more than 100 s, and discuss the pathophysiological function of the slow calcium oscillation in the neuropsychiatric disorder, especially in Parkinson's disease.
|Number of pages||9|
|Publication status||Published - 2015 Feb 1|
ASJC Scopus subject areas