Cobalt-catalyzed alkenylation of thiazoles with alkynes via C-H bond functionalization

Zhenhua Ding, Naohiko Yoshikai

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)


A cobalt-Xantphos catalyst has been developed for the syn addition of (benzo)thiazoles to internal alkynes via C-H bond functionalization. The reaction affords C2-alkenylated (benzo)thiazoles with high regio- and stereoselectivities under mild conditions.

Original languageEnglish
Article numberC29411SS
Pages (from-to)2561-2566
Number of pages6
Issue number16
Publication statusPublished - 2011
Externally publishedYes


  • C-H activation
  • alkynes
  • cobalt
  • heterocycles
  • hydroarylation

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry


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