Coating of hydroxyapatite on various substrates via hydrothermal reactions of Ca(edta)2- and phosphate

Y. Fujishiro, M. Nishino, A. Sugimori, A. Okuwaki, Tsugio Sato

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18 Citations (Scopus)


Hydroxyapatite was coated on various substrates such as 12 mol% ceria-doped tetragonal zirconia (12Ce-TZP), 3 mol% yttria-doped tetragonal zirconia (3Y-TZP), alumina, monetite coated titanium (Ti/CaHPO4) and calcium titanate coated titanium (Ti/CaTiO3) via hydrothermal reactions of Ca(edta)2- and 0.05 M NaH2PO4 at initial pH 6 and 160-200°C for 0.5-6 h. Rod-like particles of hydroxyapatite precipitated to form film on the substrates above 160°C. The morphology of the film changed significantly depending on the characteristics of substrate, i.e. hydroxyapatite entirely coated the surfaces of 12Ce-TZP, Ti/CaHPO4 and Ti/CaTiO3 plates, but sparsely deposited on 3Y-TZP and Al2O3 plates. Film thickness increased with time (ca. 20 and 90 μm on 12Ce-TZP plates for 0.5 and 6 h, respectively, at pH 6 and 200°C). The adhesive strength of the film for the substrate was in the order, 12Ce-TZP/hydroxyapatite(28MPa) > Ti/CaTiO3/hydroxyapatite (22 MPa) > Ti/CaHPO4/hydroxyapatite (9 MPa).

Original languageEnglish
Pages (from-to)333-337
Number of pages5
JournalJournal of Materials Science: Materials in Medicine
Issue number4
Publication statusPublished - 2001 Jan 1

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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