Abstract
The occurrence of large cell lymphomas subsequent to, or concurrent with, lymphocyte predominant Hodgkin's disease (LPHD) is a well-documented phenomenon. We present a case of Burkitt's lymphoma of the bladder, occurring after the successful treatment of LPHD of a cervical lymph node. To evaluate the clonal relationship of the two tumours, we amplified the complementarity-determining-region 3 of two samples from paraffin-embedded slides, using the polymerase chain reaction (PCR). The sequences of the PCR products showed 96% homology to each other. These results indicate that the malignant clone of Burkitt's lymphoma arose from the corresponding LPHD.
Original language | English |
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Pages (from-to) | 380-382 |
Number of pages | 3 |
Journal | British Journal of Haematology |
Volume | 95 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1996 Jan 1 |
Externally published | Yes |
Keywords
- Burkitt's lymphoma
- Clonality
- Hodgkin's disease
- Polymerase chain reaction
ASJC Scopus subject areas
- Hematology