Clinicopathological aspects of pancreatic cancer

Shinichi Egawa, Makoto Sunamura, Hisashi Abe, Fuyuhiko Motoi, Shoji Fukuyama, Seiki Matsuno

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Using the nationwide database of the Japan Pancreas Society (JPS), the clinicopathological features of 23,284 cases (1981-2000) and 2,298 cases (2001-2002) with pancreatic neoplasms were compared. Intraductal papillary mucinous neoplasms and mucinous cystic neoplasms were increased in the registry. More detailed histological repertoires of endocrine tumors, intraductal tubular tumors and solid-pseudopapillary tumors were registered in the last two years. The numbers of serous cystadenocarcinomas and carcinomas in situ were decreased. The proportion of less differentiated adenocarcinoma was increased in the more advanced stages of the disease. In Stage IVa, the survival of the patients with papillary adenocarcinoma was not statistically different from that of patients with well or moderate tubular adenocarcinoma, though the difference was significant in earlier stages. The survival of the patients with poorly differentiated adenocarcinoma, adenosquamous carcinoma and undifferentiated carcinoma was miserable. Histological confirmation is critically important to prospect the outcome and to determine the treatment modality. Integration of the nationwide registry and pathological information will give new insights for the treatment of pancreatic cancer.

Original languageEnglish
Pages (from-to)605-611
Number of pages7
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number5
Publication statusPublished - 2005 May

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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