Clinical studies on s 6472 granule preparation (sustained-release cefaclor) in chronic respiratory tract infections

Seiichi Aonuma, Kotaro Oizumi, Akira Watanabe, Yutaka Tokue, Yoshihiro Honda, Reiko Ono, Naoto Kitamura, Kiyoshi Konno

    Research output: Contribution to journalArticlepeer-review

    Abstract

    S 6472 granule preparation (sustained-release cefaclor) was orally administered to 15 patients with chronic respiratory tract infections (2 acutely exacerbated cases of chronic bronchitis, 13 cases of secondary infections consisting of 1 case of bronchial asthma, 2 cases of bronchial asthma/pulmonary emphysema, and 10 cases of bronchiectasis) at a daily dose of 750 mg de-vided into 2 doses administered after breakfast and dinner, for a duration of 14 days. The drug was ineffective in 3 of the 10 cases of bronchiectasis but was effective in the other 12 cases, with a rate of efficacy of 80^. There were no side effects or abnormal laboratory findings due to administration of this drug.

    Original languageEnglish
    Pages (from-to)1309-1312
    Number of pages4
    Journalthe japanese journal of antibiotics
    Volume41
    Issue number9
    DOIs
    Publication statusPublished - 1988 Jan 1

    ASJC Scopus subject areas

    • Microbiology (medical)
    • Pharmacology (medical)
    • Infectious Diseases

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