Clinical studies on s 6472 granule preparation (sustained-release cefaclor) in chronic respiratory tract infections

Seiichi Aonuma; Kotaro Oizumi; Akira Watanabe; Yutaka Tokue; Yoshihiro Honda; Reiko Ono; Naoto Kitamura; Kiyoshi Konno

doi:10.11553/antibiotics1968b.41.1309

Clinical studies on s 6472 granule preparation (sustained-release cefaclor) in chronic respiratory tract infections

Seiichi Aonuma, Kotaro Oizumi, Akira Watanabe, Yutaka Tokue, Yoshihiro Honda, Reiko Ono, Naoto Kitamura, Kiyoshi Konno

Research output: Contribution to journal › Article › peer-review

Abstract

S 6472 granule preparation (sustained-release cefaclor) was orally administered to 15 patients with chronic respiratory tract infections (2 acutely exacerbated cases of chronic bronchitis, 13 cases of secondary infections consisting of 1 case of bronchial asthma, 2 cases of bronchial asthma/pulmonary emphysema, and 10 cases of bronchiectasis) at a daily dose of 750 mg de-vided into 2 doses administered after breakfast and dinner, for a duration of 14 days. The drug was ineffective in 3 of the 10 cases of bronchiectasis but was effective in the other 12 cases, with a rate of efficacy of 80^. There were no side effects or abnormal laboratory findings due to administration of this drug.

Original language	English
Pages (from-to)	1309-1312
Number of pages	4
Journal	the japanese journal of antibiotics
Volume	41
Issue number	9
DOIs	https://doi.org/10.11553/antibiotics1968b.41.1309
Publication status	Published - 1988 Jan 1

ASJC Scopus subject areas

Microbiology (medical)
Pharmacology (medical)
Infectious Diseases

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Clinical studies on s 6472 granule preparation (sustained-release cefaclor) in chronic respiratory tract infections. / Aonuma, Seiichi; Oizumi, Kotaro; Watanabe, Akira; Tokue, Yutaka; Honda, Yoshihiro; Ono, Reiko; Kitamura, Naoto; Konno, Kiyoshi.

In: the japanese journal of antibiotics, Vol. 41, No. 9, 01.01.1988, p. 1309-1312.

Research output: Contribution to journal › Article › peer-review

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abstract = "S 6472 granule preparation (sustained-release cefaclor) was orally administered to 15 patients with chronic respiratory tract infections (2 acutely exacerbated cases of chronic bronchitis, 13 cases of secondary infections consisting of 1 case of bronchial asthma, 2 cases of bronchial asthma/pulmonary emphysema, and 10 cases of bronchiectasis) at a daily dose of 750 mg de-vided into 2 doses administered after breakfast and dinner, for a duration of 14 days. The drug was ineffective in 3 of the 10 cases of bronchiectasis but was effective in the other 12 cases, with a rate of efficacy of 80^. There were no side effects or abnormal laboratory findings due to administration of this drug.",

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