Clinical practice guideline for post-ERCP pancreatitis

Tetsuya Mine, Toshio Morizane, Yoshiaki Kawaguchi, Ryukichi Akashi, Keiji Hanada, Tetsuhide Ito, Atsushi Kanno, Mitsuhiro Kida, Hiroyuki Miyagawa, Taketo Yamaguchi, Toshihiko Mayumi, Yoshifumi Takeyama, Tooru Shimosegawa

Research output: Contribution to journalReview articlepeer-review

42 Citations (Scopus)


Background: Endoscopic retrograde cholangiopancreatography (ERPC) is used for the diagnosis and treatment of pancreatic and biliary diseases. Post-ERCP pancreatitis (PEP) is a complication which needs special care and clinical practice guideline for this morbidity is also needed. Methods: The key clinical issues of diagnosis and treatment of PEP were listed and checked, and then the clinical questions were formulated. PubMed (MEDLINE) and Ichushi-web (Japanese medical literature) were used as databases. For the study of diagnostic test accuracy, items similar to QUADAS-2, i.e., random selection from a population to which the diagnostic test is applied, blinding of index tests and reference tests, completeness of reference standard, completeness of test implementations, the same timing of tests, and missing data were assessed as well as the indirectness of the study subjects, index tests, reference standard, and outcomes. Grading of recommendations was determined as strong or weak. In clinical practice, the judgment of attending doctors should be more important than recommendations described in clinical practice guidelines. Gastroenterologists are the target users of this clinical practice guideline. General practitioners or general citizens are not supposed to use this guideline. The guideline committee has decided to include wide clinical issues such as etiological information, techniques of ERCP, the diagnosis, treatments, and monitoring of PEP in this guideline. Results: In this concise report, we described ten clinical questions, recommendations, and explanations pertaining to risk factors, diagnosis, prognostic factors, treatments, and preventive interventions in the medical practice for PEP. Conclusions: We reported here the essence of the clinical practice guideline for PEP.

Original languageEnglish
Pages (from-to)1013-1022
Number of pages10
JournalJournal of gastroenterology
Issue number9
Publication statusPublished - 2017 Sep 1


  • Clinical guideline
  • Endoscopic retrograde cholangiopancreatography (ERPC)
  • Post-ERCP pancreatitis

ASJC Scopus subject areas

  • Gastroenterology


Dive into the research topics of 'Clinical practice guideline for post-ERCP pancreatitis'. Together they form a unique fingerprint.

Cite this