Clinical Evaluation of Catheter-Related Fungemia and Bacteremia

Yuichi Inoue, Tuyoshi Fujii, Takakazu Otsubo, Norihiko Mori, Tohru Ishino, Shigeru Kohno, Tomiko Takase, Mitsuo Kaku, Hironobu Koga, Kohei Hara

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Forty-four patients with catheter-related infection admitted to Hokusho Central Hospital between 1985 and 1991 were studied retrospectively. The rate of catheter-related fungemia or bacteremia to all corresponding cases of fungemia and bacteremia increased from 7.7% in 1985 to 28.8% in 1991. The isolated pathogens were Candida parapsilosis (8 strains), Candida tropicalis (6 strains), methicillin-resistant Staphylococcus aureus (MRSA) (6 strains), methicillin-sensitive S. aureus (MSSA) (5 strains) and Streptococcus epidermidis (3 strains). Bacteremia occurred after catheterization of the femoral vein for a mean duration of 37 days. The period was significantly shorter than that after catheterization of the subclavian vein (56 days). The major isolates from the subclavian vein were Candida spp. (14/17, 82.4%), followed by MRSA (1/17, 5.9%) and MSSA (1/17, 5.9%), while isolates from the femoral vein were Candida spp. (6/16, 37.5%), MRSA (5/16, 31.3%) and MSSA (3/16, 20.8%). Catheter removal alone did not improve the clinical condition, particularly in MRSA bacteremia; the combination of antimicrobial therapy and removal of the catheter was necessary for a better prognosis.

Original languageEnglish
Pages (from-to)485-490
Number of pages6
JournalInternal Medicine
Volume34
Issue number6
DOIs
Publication statusPublished - 1995

Keywords

  • Candida spp
  • catheter-related bacteremia
  • intravenous hyperalimentation (IVH)
  • methicillin-resistant Staphylococcus aureus
  • nosocomial infection

ASJC Scopus subject areas

  • Internal Medicine

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