TY - JOUR
T1 - Clinical Evaluation of Catheter-Related Fungemia and Bacteremia
AU - Inoue, Yuichi
AU - Fujii, Tuyoshi
AU - Otsubo, Takakazu
AU - Mori, Norihiko
AU - Ishino, Tohru
AU - Kohno, Shigeru
AU - Takase, Tomiko
AU - Kaku, Mitsuo
AU - Koga, Hironobu
AU - Hara, Kohei
PY - 1995
Y1 - 1995
N2 - Forty-four patients with catheter-related infection admitted to Hokusho Central Hospital between 1985 and 1991 were studied retrospectively. The rate of catheter-related fungemia or bacteremia to all corresponding cases of fungemia and bacteremia increased from 7.7% in 1985 to 28.8% in 1991. The isolated pathogens were Candida parapsilosis (8 strains), Candida tropicalis (6 strains), methicillin-resistant Staphylococcus aureus (MRSA) (6 strains), methicillin-sensitive S. aureus (MSSA) (5 strains) and Streptococcus epidermidis (3 strains). Bacteremia occurred after catheterization of the femoral vein for a mean duration of 37 days. The period was significantly shorter than that after catheterization of the subclavian vein (56 days). The major isolates from the subclavian vein were Candida spp. (14/17, 82.4%), followed by MRSA (1/17, 5.9%) and MSSA (1/17, 5.9%), while isolates from the femoral vein were Candida spp. (6/16, 37.5%), MRSA (5/16, 31.3%) and MSSA (3/16, 20.8%). Catheter removal alone did not improve the clinical condition, particularly in MRSA bacteremia; the combination of antimicrobial therapy and removal of the catheter was necessary for a better prognosis.
AB - Forty-four patients with catheter-related infection admitted to Hokusho Central Hospital between 1985 and 1991 were studied retrospectively. The rate of catheter-related fungemia or bacteremia to all corresponding cases of fungemia and bacteremia increased from 7.7% in 1985 to 28.8% in 1991. The isolated pathogens were Candida parapsilosis (8 strains), Candida tropicalis (6 strains), methicillin-resistant Staphylococcus aureus (MRSA) (6 strains), methicillin-sensitive S. aureus (MSSA) (5 strains) and Streptococcus epidermidis (3 strains). Bacteremia occurred after catheterization of the femoral vein for a mean duration of 37 days. The period was significantly shorter than that after catheterization of the subclavian vein (56 days). The major isolates from the subclavian vein were Candida spp. (14/17, 82.4%), followed by MRSA (1/17, 5.9%) and MSSA (1/17, 5.9%), while isolates from the femoral vein were Candida spp. (6/16, 37.5%), MRSA (5/16, 31.3%) and MSSA (3/16, 20.8%). Catheter removal alone did not improve the clinical condition, particularly in MRSA bacteremia; the combination of antimicrobial therapy and removal of the catheter was necessary for a better prognosis.
KW - Candida spp
KW - catheter-related bacteremia
KW - intravenous hyperalimentation (IVH)
KW - methicillin-resistant Staphylococcus aureus
KW - nosocomial infection
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U2 - 10.2169/internalmedicine.34.485
DO - 10.2169/internalmedicine.34.485
M3 - Article
C2 - 7549129
AN - SCOPUS:0029049319
VL - 34
SP - 485
EP - 490
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 6
ER -