Clinical courses and pregnancy outcomes in Japanese women with inflammatory bowel disease

Katsuya Endo, Seiichi Takahashi, Yosuke Shimodaira, Hitoshi Nagasawa, Rintaro Moroi, Masatake Kuroha, Takashi Arai, Yoshitake Kanazawa, Hisashi Shiga, Yoichi Kakuta, Yoshitaka Kinouchi, Tooru Shimosegawa

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In this study, we analyzed the clinical courses and the pregnancy outcomes in Japanese women with inflammatory bowel disease (IBD) in our hospital in the recent 10 years. We analyzed 49 pregnancies in 38 patients with ulcerative colitis (UC) and 24 pregnancies in 16 patients with Crohn's disease (CD) retrospectively. The results indicated that pregnancy has less influence on the clinical courses of IBD and that IBD also has less influence on the pregnancy outcomes. However, we should pay attention to the results that the patients with CD tend to deteriorate if conception occurs when CD is active and that patients with active UC tend to have more adverse pregnancy outcomes than patients in remission. In conclusion, patients with IBD are recommended to become pregnant when the diseases are in remission and treatment using selected safe medications should be continued during the pregnancy.

Original languageEnglish
Pages (from-to)1858-1871
Number of pages14
JournalJournal of Japanese Society of Gastroenterology
Volume108
Issue number11
Publication statusPublished - 2011 Nov 1

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Clinical courses and pregnancy outcomes in Japanese women with inflammatory bowel disease'. Together they form a unique fingerprint.

  • Cite this

    Endo, K., Takahashi, S., Shimodaira, Y., Nagasawa, H., Moroi, R., Kuroha, M., Arai, T., Kanazawa, Y., Shiga, H., Kakuta, Y., Kinouchi, Y., & Shimosegawa, T. (2011). Clinical courses and pregnancy outcomes in Japanese women with inflammatory bowel disease. Journal of Japanese Society of Gastroenterology, 108(11), 1858-1871.