Clinical characteristics of patients with spontaneous remission of variant angina

Hideki Tashiro, Hiroaki Shimokawa, Samon Koyanagi, Akira Takeshita

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

To determine the factors influencing the spontaneous remission of variant angina, clinical characteristics were examined in 75 Japanese patients with variant angina. Spontaneous remission was defined as an absence of angina at rest for at least 3 months after withdrawal of treatment with calcium antagonists. This remission occurred in 12 patients (16%) (remission group), while angina persisted despite treatment with calcium antagonists and nitrates in 33 patients (44%) (persistent angina group). The remaining 30 patients (40%) were angina-free under treatment with calcium antagonists and/or nitrates (angina-free on treatment group). The prevalence of significant coronary artery stenosis (>75%) was significantly higher in the remission group than in the persistent angina group (44% vs 7%, p<0.05). The prevalence of cessation of smoking was significantly higher in the remission group than in the persistent angina group (92% vs 39%, p<0.01). Age, gender, other coronary risk factors, disease activity of variant angina and site of myocardial ischemia during anginal attacks were not statistically different among the 3 groups. There data indicate that remission of variant angina occurs more frequently in patients with than in those without significant coronary artery stenosis and that cessation of smoking is an important factor for remission of variant angina.

Original languageEnglish
Pages (from-to)117-122
Number of pages6
JournalJAPANESE CIRCULATION JOURNAL
Volume57
Issue number2
DOIs
Publication statusPublished - 1993
Externally publishedYes

Keywords

  • Coronary arteryspasm
  • Spontaneous remission
  • Variant angina

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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