Clinical and laboratory features of neuromyelitis optica with oligoclonal IgG bands

Masashi Nakamura, I. Nakashima, S. Sato, I. Miyazawa, K. Fujihara, Y. Itoyama

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Of 23 neuromyelitis optica (NMO) cases, we found two cases with oligoclonal IgG bands (OBs). Both patients were positive for NMO-IgG. Their common features were long disease duration and coexisting autoimmune diseases (myasthenia gravis and sicca syndrome). Although OBs are mostly negative in NMO, which distinguishes it from multiple sclerosis (MS) they can be positive by long-standing autoimmunity, which may not be directly related to NMO.

Original languageEnglish
Pages (from-to)332-335
Number of pages4
JournalMultiple Sclerosis
Volume13
Issue number3
DOIs
Publication statusPublished - 2007 Apr

Keywords

  • Co-existing autoimmune diseases
  • Myasthenia gravis
  • NMO-lgG
  • Neuromyelitis optica
  • Oligoclonal lgG bands
  • Sicca syndrome

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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