TY - JOUR
T1 - Clinical and laboratory features of neuromyelitis optica with oligoclonal IgG bands
AU - Nakamura, Masashi
AU - Nakashima, I.
AU - Sato, S.
AU - Miyazawa, I.
AU - Fujihara, K.
AU - Itoyama, Y.
PY - 2007/4
Y1 - 2007/4
N2 - Of 23 neuromyelitis optica (NMO) cases, we found two cases with oligoclonal IgG bands (OBs). Both patients were positive for NMO-IgG. Their common features were long disease duration and coexisting autoimmune diseases (myasthenia gravis and sicca syndrome). Although OBs are mostly negative in NMO, which distinguishes it from multiple sclerosis (MS) they can be positive by long-standing autoimmunity, which may not be directly related to NMO.
AB - Of 23 neuromyelitis optica (NMO) cases, we found two cases with oligoclonal IgG bands (OBs). Both patients were positive for NMO-IgG. Their common features were long disease duration and coexisting autoimmune diseases (myasthenia gravis and sicca syndrome). Although OBs are mostly negative in NMO, which distinguishes it from multiple sclerosis (MS) they can be positive by long-standing autoimmunity, which may not be directly related to NMO.
KW - Co-existing autoimmune diseases
KW - Myasthenia gravis
KW - NMO-lgG
KW - Neuromyelitis optica
KW - Oligoclonal lgG bands
KW - Sicca syndrome
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U2 - 10.1177/13524585070130030201
DO - 10.1177/13524585070130030201
M3 - Article
C2 - 17439901
AN - SCOPUS:34248223658
VL - 13
SP - 332
EP - 335
JO - Multiple Sclerosis Journal
JF - Multiple Sclerosis Journal
SN - 1352-4585
IS - 3
ER -