Clinical and histological features of cytomegalovirus hepatitis in previously healthy adults

Atsushi Kanno, Masahide Abe, Miki Yamada, Kazuhiro Murakami

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

It is well known that cytomegalovirus infection is often accompanied by hepatitis, but there have been few comparative studies with respect to clinical features of cytomegalovirus-associated hepatitis and other acute viral hepatitides. In the present study, clinical and pathological features of 11 acute sporadic cytomegalovirus hepatitis infections in previously healthy adults were compared with those of 45 acute sporadic viral hepatitis, including type A, type B and type C. As a result, the characteristics of cytomegalovirus hepatitis were a long-lasting fever, splenomegaly, atypical lymphocytosis, a mild transaminasemia, a low ratio of alanine aminotransferase level to lactate dehydrogenase level, and mild hepatic histopathological changes.

Original languageEnglish
Pages (from-to)129-132
Number of pages4
JournalLiver
Volume17
Issue number3
Publication statusPublished - 1997 Jun 1
Externally publishedYes

Keywords

  • Acute hepatitis
  • Cytomegalovirus
  • Healthy adult

ASJC Scopus subject areas

  • Hepatology

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