Cleveland clinic PediPump lamb cadaver fitting studies

Faruk Cingoz, Kiyotaka Fukamachi, Yoshio Ootaki, Keiji Kamohara, Masatoshi Akiyama, Chiyo Ootaki, Michael W. Kopcak, Jenny Liu, Angela Noecker, Dave Dudzinski, William A. Smith, Brian W. Duncan

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

We are developing the PediPump, a magnetically suspended, mixed-flow pump, as an implantable pediatric ventricular assist device (VAD). Lamb cadaver fitting studies were performed to determine the optimal pump location and optimal design of the inflow and outflow conduits for chronic in vivo studies. A prototype of the PediPump right and left ventricular assist devices (RVAD and LVAD, respectively) were implanted via a sternotomy or left thoracotomy in four lamb cadavers (3.7-34.2 kg). Via a sternotomy, the RVAD and LVAD required long inflow cannulas when placed into the right or left thoracic cavities, respectively. Via a left thoracotomy, with both pumps implanted in the left thoracic cavity, the RVAD required a 70°inflow cannula and a bent outflow graft while the LVAD required a 130°inflow cannula and a straight outflow graft. In conclusion, left thoracotomy provided optimal fitting for both LVAD and RVAD for the small lamb model.

Original languageEnglish
Pages (from-to)405-408
Number of pages4
JournalArtificial Organs
Volume31
Issue number5
DOIs
Publication statusPublished - 2007 May 1
Externally publishedYes

Keywords

  • Circulatory support
  • Fitting study
  • Pediatrics
  • Ventricular assist device

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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