TY - JOUR
T1 - Clear cell acanthoma developing in epidermal nevus
AU - Yamasaki, Kenshi
AU - Hatamochi, Atsushi
AU - Shinkai, Hiroshi
AU - Manabe, Toshiaki
PY - 1997/1/1
Y1 - 1997/1/1
N2 - A 33-year-old Japanese woman presented with a black papule on a pigmented lesion which had been on her right thigh since her early childhood. A hematoxylin-eosin-stained section revealed a sharply demarcated, acanthotic epidermis composed of enlarged clear cells, which stained positively for epithelial membrane antigen and negatively for carcinoembryonic antigen. With antikeratin antibodies, the tumor cells stained for AE1 and AE3, but did not stain for CAM5.2. They contained abundant glycogen. Histologically, we diagnosed the case as a clear cell acanthoma which developed in the pre- existing epidermal nevus. This is the second such case in the literature.
AB - A 33-year-old Japanese woman presented with a black papule on a pigmented lesion which had been on her right thigh since her early childhood. A hematoxylin-eosin-stained section revealed a sharply demarcated, acanthotic epidermis composed of enlarged clear cells, which stained positively for epithelial membrane antigen and negatively for carcinoembryonic antigen. With antikeratin antibodies, the tumor cells stained for AE1 and AE3, but did not stain for CAM5.2. They contained abundant glycogen. Histologically, we diagnosed the case as a clear cell acanthoma which developed in the pre- existing epidermal nevus. This is the second such case in the literature.
KW - Antikeratin antibody
KW - CEA
KW - Clear cell acanthoma
KW - EMA
KW - Epidermal nevus
UR - http://www.scopus.com/inward/record.url?scp=9844221407&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=9844221407&partnerID=8YFLogxK
U2 - 10.1111/j.1346-8138.1997.tb02300.x
DO - 10.1111/j.1346-8138.1997.tb02300.x
M3 - Article
C2 - 9350108
AN - SCOPUS:9844221407
SN - 0385-2407
VL - 24
SP - 601
EP - 605
JO - Journal of Dermatology
JF - Journal of Dermatology
IS - 9
ER -