Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: A consensus study

Toru Furukawa, Günter Klöppel, N. Volkan Adsay, Jorge Albores-Saavedra, Noriyoshi Fukushima, Akira Horii, Ralph H. Hruban, Yo Kato, David S. Klimstra, Daniel S. Longnecker, Jutta Lüttges, G. Johan A. Offerhaus, Michio Shimizu, Makoto Sunamura, Arief Suriawinata, Kyoichi Takaori, Suguru Yonezawa

Research output: Contribution to journalArticlepeer-review

533 Citations (Scopus)


Now that more than two decades have passed since the first reports of intraductal papillary-mucinous neoplasms (IPMNs), it has become clear that IPMN consists of a spectrum of neoplasms with both morphological and immunohistochemical variations. At a meeting of international experts on pancreatic precursor lesions held in 2003, it was agreed that a consensus classification of IPMN subtypes should be established to enable a more detailed analysis of the clinicopathological significance of the variations. Based on our experience and on information from the literature, we selected representative histological examples of IPMNs and defined a consensus nomenclature and criteria for classifying variants as distinctive IPMN subtypes including gastric type, intestinal type, pancreatobiliary type, and oncocytic type. These definitions can be used for further analyses of the clinicopathological significance of the variations of IPMN.

Original languageEnglish
Pages (from-to)794-799
Number of pages6
JournalVirchows Archiv
Issue number5
Publication statusPublished - 2005 Nov


  • Classification
  • Intraductal papillary-mucinous neoplasm
  • MUC
  • Pancreatic tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Cell Biology


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