TY - GEN
T1 - Circular dichroism thermal lens microscope for sensitive and selective detection of chiral samples on microchip
AU - Mawatari, Kazuma
AU - Yamauchi, Masayo
AU - Hibara, Akihide
AU - Tokeshi, Manabu
AU - Kitamori, Takehiko
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2005
Y1 - 2005
N2 - Thermal lens microscope (TLM) is a kind of absorption spectrometry with a sensitivity of single molecules in fL detection volume. In this paper, we report a newly functionalized TLM for selective and sensitive detection of chiral samples. We developed a circular dichroism (CD) thermal lens microscope by light phase modulation. We verified the basic principle and achieved two orders higher sensitivity than CD spectrometer.
AB - Thermal lens microscope (TLM) is a kind of absorption spectrometry with a sensitivity of single molecules in fL detection volume. In this paper, we report a newly functionalized TLM for selective and sensitive detection of chiral samples. We developed a circular dichroism (CD) thermal lens microscope by light phase modulation. We verified the basic principle and achieved two orders higher sensitivity than CD spectrometer.
KW - Circular dichroism
KW - Non-fluorescent molecules
KW - Thermal lens microscope
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M3 - Conference contribution
AN - SCOPUS:84902457153
SN - 0974361119
SN - 9780974361116
T3 - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 1035
EP - 1037
BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
PB - Transducer Research Foundation
T2 - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
Y2 - 9 October 2005 through 13 October 2005
ER -