[Circadian blood pressure variation under several pathophysiological conditions including secondary hypertension].

Yutaka Imai, Miki Hosaka, Michihiro Satoh

Research output: Contribution to journalReview article

Abstract

Abnormality of circadian blood pressure (BP) variation, i.e. non-dipper, riser, nocturnal hypertension etc, is brought by several pathophysiological conditions especially by secondary hypertension. These pathophysiological conditions are classified into several categories, i.e. disturbance of autonomic nervous system, metabolic disorder, endocrine disorder, disorder of Na and water excretion (e.g. sodium sensitivity), severe target organ damage and ischemia, cardiovascular complications and drug induced hypertension. Each pathophysiological condition which brings disturbance of circadian BP variation is included in several categories, e.g. diabetes mellitus is included in metabolic disorder, autonomic imbalance, sodium sensitivity and endocrine disorder. However, it seems that unified principle of the genesis of disturbance of circadian BP variation in many pathophysiological conditions is autonomic imbalance. Thus, it is concluded that disturbance of circadian BP variation is not purposive biological behavior but the result of autonomic imbalance which looks as if compensatory reaction such as exaggerated Na-water excretion during night in patient with Na-water retention who reveals disturbed circadian BP variation.

Original languageEnglish
Pages (from-to)1429-1434
Number of pages6
JournalNihon rinsho. Japanese journal of clinical medicine
Volume72
Issue number8
Publication statusPublished - 2014 Jan 1

ASJC Scopus subject areas

  • Medicine(all)

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