Abstract
Two new hydroxycitric acid lactone derivatives named cinatrins D (1) and E (2), and a new γ-lactam, virgaricin B (3), along with a known similar compound, virgaricin (4), were isolated from a fermentation broth of the fungus Virgaria boninensis FKI-4958. The absolute stereo structures of the new compounds were established by a combination of spectroscopic methods and chemical modifications. All three newly discovered compounds possessed weak antibacterial activity.
Original language | English |
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Pages (from-to) | 633-637 |
Number of pages | 5 |
Journal | Journal of Antibiotics |
Volume | 68 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2015 Oct 1 |
Externally published | Yes |
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery