TY - JOUR
T1 - Chronic Granulomatous Disease with Neutrophil Membrane Cytochrome B Deficiency
T2 - Demonstration by Immunochemical Staining with Monoclonal Antibody
AU - Minegishi, Naoko
AU - Suzaki, Ken
AU - Terasawa, Masahiko
AU - Minegishi, Masayoshi
AU - Tsuchiya, Shigeru
AU - Konno, Tasuke
AU - Nakamura, Michio
PY - 1988
Y1 - 1988
N2 - Cytochrome b deficicency in the peripheral granulocytes of two male patients with chronic granulomatous disease was demonstrated by an immunocytochemical assay using a monoclonal antibody, 7D5, against human neutrophil cytochrome b. A mosaic of cytochrome b positive and negative neutrophils, indicating a carrier state in an X-linked trait, was found in the mother of patient 1 but not in the mother of patient 2.
AB - Cytochrome b deficicency in the peripheral granulocytes of two male patients with chronic granulomatous disease was demonstrated by an immunocytochemical assay using a monoclonal antibody, 7D5, against human neutrophil cytochrome b. A mosaic of cytochrome b positive and negative neutrophils, indicating a carrier state in an X-linked trait, was found in the mother of patient 1 but not in the mother of patient 2.
KW - chronic granuromatous disease
KW - cytochrome b
KW - leukocyte
UR - http://www.scopus.com/inward/record.url?scp=0023934666&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023934666&partnerID=8YFLogxK
U2 - 10.1620/tjem.154.143
DO - 10.1620/tjem.154.143
M3 - Article
C2 - 3381223
AN - SCOPUS:0023934666
VL - 154
SP - 143
EP - 148
JO - Tohoku Journal of Experimental Medicine
JF - Tohoku Journal of Experimental Medicine
SN - 0040-8727
IS - 2
ER -
