Choroid plexus papillomas: An immunohistochemical study with particular reference to the coexpression of prealbumin

T. Matsushima, T. Inoue, I. Takeshita, M. Fukui, T. Iwaki, T. Kitamoto

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Immunocytochemical characterization of choroid plexus neoplasms was performed in seven cases, five being of benign choroid plexus papilloma (CPP) and the other two of malignant choroid plexus papilloma (choroid plexus carcinoma (CPC). Immunohistochemical examination was performed with antibodies to glial fibrillary acidic protein (GFAP), S-100 protein, prealbumin, carcinoembryonic antigen (CEA), epithelial membrane antigen (EMA), and γ-enolase. All of the five CPPs were positive for GFAP, S-100, prealbumin, and γ-enolase; and four of them were positive for EMA. None of the CPPs was positive for CEA. Both of the two cases of CPC were positive for γ-enolase, and one was positive for GFAP, S-100, EMA, and CEA. No CPC showed positivity for prealbumin. This report is the first to describe the usefulness of prealbumin reactivity for histological diagnosis of choroid plexus papillomas.

Original languageEnglish
Pages (from-to)384-389
Number of pages6
JournalNeurosurgery
Volume23
Issue number3
DOIs
Publication statusPublished - 1988 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Choroid plexus papillomas: An immunohistochemical study with particular reference to the coexpression of prealbumin'. Together they form a unique fingerprint.

  • Cite this