Chondrosarcoma: Its treatment by radiation, hyperthermia and bleomycin

S. Okuyama, M. Itoh, K. Tanaka, T. Matsuzawa

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

A case of chondrosarcoma of the mandible of surgical failure was treated by radiation, hyperthermia, and bleomycin. The treatment resulted in selective necrosis of the tumor. This can be designated as perpetuation principle of radiothermotherapy because bleomycin may inhibit the repair processes of heat and radiation damage. This principle appears to offer selectivity of the therapeutic effects, to open a way to treatment of those radioresistant selectivity of the therapeutic effects, open a way to treatment of those radioresistant malignancies, and to enhance curability of various medium-sensitive tumors. Additionally, a course of large-dose glutathione infusion was confirmed to promptly alleviate radiation dermatitis and mucositis.

Original languageEnglish
Pages (from-to)83-88
Number of pages6
JournalScience Reports of the Research Institutes Tohoku University - Series C Medicine
Volume25
Issue number3-4
Publication statusPublished - 1978 Dec 1

ASJC Scopus subject areas

  • Medicine(all)

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