Abstract
A chiral tetraazamacrocycle 9 having four pendant-arms was synthesized by repeating ring opening of an Ns-aziridine with secondary amines, followed by macrocyclization. The structure of 9 has been determined by single crystal X-ray diffraction analysis and NMR studies. Sugarhybrid molecules 12a-12f were synthesized based on the scaffold 9. NMR study showed that 12a-12f keep the similar conformation as 9 in solution.
Original language | English |
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Pages (from-to) | 2289-2292 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 11 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2009 Jun 4 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry