Chiral tetraazamacrocycles having four pendant-arms

Seiji Kamioka, Takashi Takahashi, Susumu Kawauchi, Hiroaki Adachi, Yusuke Mori, Kotaro Fujii, Hidehiro Uekusa, Takayuki Doi

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


A chiral tetraazamacrocycle 9 having four pendant-arms was synthesized by repeating ring opening of an Ns-aziridine with secondary amines, followed by macrocyclization. The structure of 9 has been determined by single crystal X-ray diffraction analysis and NMR studies. Sugarhybrid molecules 12a-12f were synthesized based on the scaffold 9. NMR study showed that 12a-12f keep the similar conformation as 9 in solution.

Original languageEnglish
Pages (from-to)2289-2292
Number of pages4
JournalOrganic letters
Issue number11
Publication statusPublished - 2009 Jun 4

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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