Abstract
An enantioselective intermolecular carbonyl-ene reaction and a Friedel-Crafts-type reaction of 1,1,2-trisubstituted and 1,2-disubstituted simple olefins with ethyl glyoxylate were developed using F10BINOL-derived N-sulfonyl phosphoramide as the chiral strong Brønsted acid catalyst. The present reactions feature an atom-economical and environmentally benign approach to the synthesis of enantioenriched allylic and homoallylic alcohols.
Original language | English |
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Pages (from-to) | 1383-1387 |
Number of pages | 5 |
Journal | Organic Chemistry Frontiers |
Volume | 7 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2020 Jun 7 |
ASJC Scopus subject areas
- Organic Chemistry