Chemospecific allylation and domino metathesis of 7-oxanorbornenes for skeletal and appendage diversity

Minoru Ikoma; Masato Oikawa; Makoto Sasaki

doi:10.1002/ejoc.200800781

Chemospecific allylation and domino metathesis of 7-oxanorbornenes for skeletal and appendage diversity

Minoru Ikoma, Masato Oikawa, Makoto Sasaki

LIF - Molecular and Chemical Life Science

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

We report a synthetic strategy for skeletally diverse heterocycles featuring appendage diversity based on a tandem Ugi/ Diels-Alder reaction followed by domino metathesis. An associating effect of the amide carbonyl functionality to the ruthenium metal center is proposed in order to account for the difference in the metathesis yields.

Original language	English
Pages (from-to)	72-84
Number of pages	13
Journal	European Journal of Organic Chemistry
Issue number	1
DOIs	https://doi.org/10.1002/ejoc.200800781
Publication status	Published - 2009 Jan

Keywords

Alkylation
Combinatorial chemistry
Domino reactions
Metathesis
Multicomponent reactions

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Organic Chemistry

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10.1002/ejoc.200800781

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abstract = "We report a synthetic strategy for skeletally diverse heterocycles featuring appendage diversity based on a tandem Ugi/ Diels-Alder reaction followed by domino metathesis. An associating effect of the amide carbonyl functionality to the ruthenium metal center is proposed in order to account for the difference in the metathesis yields.",

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KW - Domino reactions

KW - Metathesis

KW - Multicomponent reactions

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Chemospecific allylation and domino metathesis of 7-oxanorbornenes for skeletal and appendage diversity

Abstract

Keywords

ASJC Scopus subject areas

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