TY - JOUR
T1 - Chemical synthesis of cellulose and cello-oligomers using a hydrolysis enzyme as a catalyst
AU - Kobayashi, Shiro
AU - Shoda, Shin ichiro
N1 - Funding Information:
This work was partly supported by a Grant-in-Aid for Scientific Research (No. 06403026) and a Grant-in-Aid for Scientific Research on Priority Areas (No. 06240205) from the Ministry of Education, Science and Culture, Japan.
PY - 1995
Y1 - 1995
N2 - Regio- and stereo-selective synthesis of polysaccharides and oligosaccharides has been achieved by using glycosyl fluorides as substrates for cellulases. This methodology has successfully been applied to the first synthesis of cellulose via a non-biosynthetic pathway as well as to a selective preparation of cello-oligosaccharides and unnatural oligosaccharides. Using the enzymatic polymerization, it is possible to control the relative direction (parallel or anti-parallel) of each glucan chain in the synthetic cellulose in vitro. Based on these results, a new concept of 'allos-selectivity' in polymer synthesis has been proposed.
AB - Regio- and stereo-selective synthesis of polysaccharides and oligosaccharides has been achieved by using glycosyl fluorides as substrates for cellulases. This methodology has successfully been applied to the first synthesis of cellulose via a non-biosynthetic pathway as well as to a selective preparation of cello-oligosaccharides and unnatural oligosaccharides. Using the enzymatic polymerization, it is possible to control the relative direction (parallel or anti-parallel) of each glucan chain in the synthetic cellulose in vitro. Based on these results, a new concept of 'allos-selectivity' in polymer synthesis has been proposed.
KW - cellulase
KW - cellulose I
KW - enzymatic polymerization
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U2 - 10.1016/0141-8130(96)81849-6
DO - 10.1016/0141-8130(96)81849-6
M3 - Article
C2 - 8789343
AN - SCOPUS:0029614678
VL - 17
SP - 373
EP - 379
JO - International Journal of Biological Macromolecules
JF - International Journal of Biological Macromolecules
SN - 0141-8130
IS - 6
ER -