Chemical structures of three neutral oligosaccharides obtained from horse (thoroughbred) colostrum

Tadasu Urashima, Tadao Saito, Tsutomu Kimura

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

1. 1. Three neutral oligosaccharides were obtained from horse colostrum by ion-exchange, activated charcoal column and preparative paper chromatographies. 2. 2. The following structures were elucidated by methanolysis, methylation analysis and 75 MHz 13C-NMR spectroscopy; Galβ1-4GlcNAcβ1-3Galβ1-4Glc (HM-3a), Galβ1-4GlcNAcβ1-6Galβ1-4Glc (HM-3b) and Galβ1-4GlcNAcβ1-3[Galβ1-4GlcNAcβ1-6]Galβ1-4Glc (HM-5). 3. 3. HM-3a and HM-5 have been found in human milk, named as lacto-N-neotetraose and lacto-N-neohexaose, respectively. HM-3b has been isolated from goat milk. 4. 4. An homology and heterogeneity were assumed among the following animal species' milk oligosaccharides: horse, human, goat and tammar wallaby.

Original languageEnglish
Pages (from-to)177-183
Number of pages7
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume100
Issue number1
DOIs
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology

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