Chemical processing on microchips for analysis, synthesis, and bioassay

Manabu Tokeshi, Yoshikuni Kikutani, Akihide Hibara, Kiichi Sato, Hideaki Hisamoto, Takehiko Kitamori

Research output: Contribution to journalReview articlepeer-review

50 Citations (Scopus)


This review describes our recent research on miniaturization of chemical systems. We have developed a miniaturization methodology based on pressure-driven multiphase laminar flow and a highly sensitive detection tool, the thermal lens microscope. Some representative applications of the methodology in the fields of analysis, synthesis, and bioassay are described.

Original languageEnglish
Pages (from-to)3583-3594
Number of pages12
Issue number21
Publication statusPublished - 2003 Nov
Externally publishedYes


  • Continuous-flow chemical processing
  • Microunit operation
  • Miniaturization
  • Multiphase laminar flow
  • Pressure-driven flow
  • Review
  • Thermal lens microscope

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry


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