Chemical characterisation of six oligosaccharides in a sample of colostrum of the brown capuchin, Cebus apella (Cebidae: Primates)

Tadasu Urashima, Yuhko Kawai, Tadashi Nakamura, Ikichi Arai, Tadao Saito, Misako Namiki, Koh ichi Yamaoka, Kazuyuki Kawahawa, Michael Messer

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

Carbohydrates were extracted from a sample of brown capuchin colostrum and six of the component oligosaccharides were separated and purified by gel filtration and preparative thin layer chromatography. Their structures were determined by 1H-NMR to be as follows: Gal β 1→4[Fuc α 1→3]Glc (3- fucosyllactose) Gal β 1→3Gal β 1→4Glc (β-3'-galactosyllactose) Gal β 1→6Gal β 1→4Glc (β-6'-galactosyllactose) Gal β 1→3[Gal β 1→4GlcNAc β 1→6]Gal β 1→4Glc (lacto-N-novopentaose I) Gal β 1→4GlcNAc β 1→3[Gal β 1→4GlcNAc β 1→6]Gal β 1→4Glc (lacto-N-neohexaose) Neu5Ac α 2→3Gal β 1→4Glc (3'-N-acetylneuraminyllactose) Of these, all except lacto-N- novopentaose I have been previously found in human milk or colostrum.

Original languageEnglish
Pages (from-to)295-300
Number of pages6
JournalComparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology
Volume124
Issue number3
DOIs
Publication statusPublished - 1999 Nov

Keywords

  • Cebus apella
  • Chemical structure
  • Colostrum
  • H-NMR
  • Lactose
  • Milk
  • New world monkey
  • Oligosaccharide
  • Primate

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

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