Abstract
The specificity of monoclonal antibodies directed against the Salmonella minnesota R595 lipid A and the structural requirements of lipid A epitopes were studied with chemically synthesized lipid A analogues by enzyme-linked immunosorbent assay and its inhibition test. The results suggest that lipid A has specific and common epitopes, in which the specificities are derived from the chemical and conformational structures of the backbone and/or acyl groups.
Original language | English |
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Pages (from-to) | 479-482 |
Number of pages | 4 |
Journal | FEMS Microbiology Letters |
Volume | 49 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1988 Mar |
Keywords
- Lipid A epitope
- Monoclonal antibody
- Synthetic lipid A analogue
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
- Genetics