Characterisation of sugar nucleotides in colostrum of dairy domestic farms animals

Yuri Mineguchi, Kyosuke Goto, Yuna Sudo, Kentaro Hirayama, Hirotoshi Kashiwagi, Izumi Sasagase, Haruki Kitazawa, Sadaki Asakuma, Kenji Fukuda, Tadasu Urashima

Research output: Contribution to journalArticlepeer-review

Abstract

The biological significance and heterogeneity of bovine, caprine and ovine colostrum sugar nucleotides is unclear. Colostrum sugar nucleotides and sugar monophosphates were purified and characterised with 1H-NMR spectroscopy. UDP-galactose (UDP-Gal) and UDP-glucose (UDP-Glc) were identified in colostrum of Holstein and Brown Swiss cows; UDP-Gal, UDP-Glc, UDP-N-acetylgalactosamine (UDP-GalNAc) and UDP-N-acetylglucosamine (UDP-GlcNAc) were found in Japanese Saanen goat colostrum. UDP-Gal, UDP-Glc, UDP-GalNAc and UDP-GlcNAc were found in Corriedale sheep but not in the Suffolk and Fraise Land breeds. The presence/absence of these sugar nucleotides in colostrum is heterogeneous among dairy domestic farm animals and the three sheep breeds. In addition, a nucleotide, uridine-ribose diphosphate (UDP) was identified in the colostra of Japanese Saanen goat, and Suffolk and Fraiseland sheep, while uridine-ribose monophosphate (UMP) was detected in the colostrum of Brown Swiss cow and the three breed sheep. N-acetylglucosamine-1-phosphate (GlcNAc-1-P) was also identified in the colostrum of the goat and two cow breeds.

Original languageEnglish
Article number104897
JournalInternational Dairy Journal
Volume113
DOIs
Publication statusPublished - 2021 Feb

ASJC Scopus subject areas

  • Food Science
  • Applied Microbiology and Biotechnology

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