Changes in circulating adiponectin and metabolic hormone concentrations during periparturient and lactation periods in Holstein dairy cows

Yoshihisa Ohtani, Tatsuyuki Takahashi, Katsuyoshi Sato, Astrid Ardiyanti, Sang Houn Song, Reiichiro Sato, Ken Onda, Yasunori Wada, Yoshiaki Obara, Keiichi Suzuki, Akihiko Hagino, Sang Gun Roh, Kazuo Katoh

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Although our previous report demonstrated that adiponectin and AdipoR1 gene expressions changed among different lactation stages in the bovine mammary gland, its in vivo kinetics remain unclear in ruminant animals. In this study, we investigated the changes in circulating concentrations of adiponectin, as well as other metabolic hormones and metabolites, (i) during the periparturient period and (ii) among different lactation stages, in Holstein dairy cows. In experiment 1, serum adiponectin concentrations increased after parturition. Serum insulin concentrations were lower in the postpartum than prepartum period, whereas serum growth hormone (GH) concentrations increased in the postpartum period. Serum nonesterified fatty acids (NEFA) levels were increased during the postpartum period and were dependent on the parity. In experiment 2, there was no significant difference in plasma adiponectin concentrations among lactational stages. Plasma insulin concentrations tended to be lower in early lactation while plasma GH levels tended to be higher. Plasma NEFA concentrations were significantly lower in mid- and late-lactation stages than non-lactation stages. These findings indicate that elevation of serum adiponectin might be involved in energy metabolism just around parturition, and might exert its action through regulation of receptor expression levels in target tissues in each lactational stage in Holstein dairy cows.

Original languageEnglish
Pages (from-to)788-795
Number of pages8
JournalAnimal Science Journal
Volume83
Issue number12
DOIs
Publication statusPublished - 2012 Dec

Keywords

  • Adiponectin
  • Dairy cows
  • Growth hormone
  • Insulin

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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