Changes in arterial oxygen tenssion during and after enflurane or halothane anesthesia as well as epidural analgesia

K. Hoshi, T. Shima, K. Andoh, S. Matsukawa, Y. Hashimoto

Research output: Contribution to journalArticlepeer-review

Abstract

Recovery from inhalation anesthesia is often marked by the occurrence of postoperative hypoxemia. In this study, we compared the effects of enflurane or halothane anesthesia and epidural analgesia on arterial oxygen tenssion during and after the operation in 60 ASA physical status 1-2 patients who underwent cholecystectomy. Anesthesia was induced with thiopental and maintained with 66% N2O and -enflurane (1.5%), -halothane (1%), or -epidural lidocaine (1% solution, 17.5ml) in oxygen. Blood gas analysis was done before and 10, 30, 60 min after induction. Pa(O)2 was measured on 1st and 3rd postoperative days in all patients breathing air spontaneously. Pa(O)2 decreased during operation in all three groups of anesthesia. Pa(O)2 values on first postoperative day were significantly lower than those before operation, and Pa(O)2 value in enflurane group (Pa(O)2=67±1mmHg) was significantly lower than that in halothane group (Pa(O)2=72±2mmHg, P<0.05).

Original languageEnglish
Pages (from-to)910-914
Number of pages5
JournalJapanese Journal of Anesthesiology
Volume39
Issue number7
Publication statusPublished - 1990 Jan 1

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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