Abstract
Azadirachtin is a complex natural product, which possesses sixteen contiguous stereogenic centers as well as various oxygen-containing functional groups. Completing the synthesis of this compound is one of the greatest challenges for synthetic chemists. It took about twenty-six years for us to achieve the second synthesis of azadirachtin in the world. In this article, I wish to describe the details of our synthetic studies on azadirachtin.
Original language | English |
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Pages (from-to) | 506-509 |
Number of pages | 4 |
Journal | Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry |
Volume | 76 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2018 Jan 1 |
Externally published | Yes |
Keywords
- Azadirachtin
- Insect antifeedant
- Natural products
- Radical cyclization
- Total synthesis
ASJC Scopus subject areas
- Organic Chemistry