Cerebral blood oxygenation changes during ventricular assitance with vibrating flow pump

T. Yambe, S. Kobayashi, N. Owada, S. Nanka, S. Nitta, M. Yoshizawa, H. Hashimoto

Research output: Contribution to journalConference articlepeer-review


Aiming at a totally implantable type ventricular assist device (VAD), we adopted the design concept of short stroke volume and high frequency. The transcutaneous energy transmission system (TETS) using the amorphous fiber was developed to constitute the totally implantable VAS system. Vibrating flow pump (VFP), which was developed by the concept of short stroke volume, works with high frequency compared with a natural heart of a biological system. It is frequency of 10-50 Hz. In this research, the animal experiments of the left ventricular assistance were carried out with the healthy adult goats. All hemodynamic data were stored in the magnetic tape and analyzed in the computer system through the AD converter. TETS with amorphous fibers showed enough performance and temperature rise were not so significant. During left heart bypass with VFP, cerebral blood oxygenation was measured with Near infrared oxygenation monitoring equipment (NIRO). As the results, according to an alteration of the drive frequency, cerebral blood oxygen saturation was significantly altered, even during same total cardiac output and same bypass ratio. This result suggested the altered brain blood flow. Thus, it may be possible to control the brain blood flow by the selection of the drive frequency of VAD. We want to continue the development toward the one of the candidates of the totally implantable VAD.

Original languageEnglish
Pages (from-to)162
Number of pages1
JournalASAIO Journal
Issue number2
Publication statusPublished - 2000
Event46th Annual Conference and Exposition of ASAIO - New York, NY, USA
Duration: 2000 Jun 282000 Jul 1

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering


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