Cerebral blood flow and metabolism following superficial temporal artery to superior cerebellar artery bypass for vertebrobasilar occlusive disease

A. Ogawa, M. Kameyama, K. Muraishi, T. Yoshimoto, Masatoshi Itoh, Y. Sakurai

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

In order to clarify the effectiveness of extracranial-intracranial bypass operations in patients with vertebrobasilar occlusive disease, the authors used positron emission tomography to investigate the cerebral blood flow (CBF) and metabolism of eight patients undergoing superficial temporal artery (STA)-superior cerebellar artery (SCA) bypass procedures. In the preoperative studies, CBF in the region of the posterior fossa was low and the oxygen extraction fraction (OEF) was high, the so-called 'misery perfusion syndrome.' Such changes were evident in both the posterior circulation and the anterior circulation regions. Postoperatively, there was a significant increase in CBF, a significant decrease in the OEF not only in the region of posterior circulation but also over the entire brain, and a disappearance of the uncoupling between CBF and oxygen metabolism. The STA-SCA bypass procedure is effective in improving CBF and metabolism in patients with vertebrobasilar occlusive disease.

Original languageEnglish
Pages (from-to)955-960
Number of pages6
JournalJournal of neurosurgery
Volume76
Issue number6
DOIs
Publication statusPublished - 1992 Jan 1

Keywords

  • cerebral blood flow
  • cerebral infarction
  • extracranial-intracranial bypass
  • positron emission tomography
  • vertebrobasilar insufficiency

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Cerebral blood flow and metabolism following superficial temporal artery to superior cerebellar artery bypass for vertebrobasilar occlusive disease'. Together they form a unique fingerprint.

  • Cite this